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Analysis of the Composition of the Intestinal Microbiota in Patients Post-intestinal Anastomosis

Recruitingn/aAges 18 Years - anyAllInstituto de Investigación Sanitaria de la Fundac…
NCT07416760 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower microbial diversity. Considering the bibliographic data, our main interest is to analyze the microbial population of patients in our social environment and then look for differences in the microbiome between those who have suffered an anastomotic dehiscence (around 8-9% according to the results of our hospital's Surgery Department) and those who have not.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients who have undergone colorectal intestinal anastomosis. * Signing of the informed consent form. * Age ≥18 years with good functional status. * Availability for postoperative follow-up. Exclusion Criteria: * Emergency surgery. * Intra-abdominal sepsis or previous dehiscence. * Severe immunosuppression. * Use of antibiotics in the 3 months prior to preoperative preparation. * Pregnancy or breastfeeding.
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What it tests

  • Not applicable- observational study
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Where

1 site
University Hospital Fundación Jiménez Díaz
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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