AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Effect of Maternal Chocolate Consumption on Fetal Non-Stress Test (NST) Reactivity.

RecruitingNAAges 18 Years - 49 YearsFemaleUniversidad Nacional Autonoma de Honduras
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This is a single-blind, randomized, parallel-group, superiority clinical trial. The study aims to determine whether a single intake of 30g of dark chocolate (โ‰ฅ80% cocoa) by pregnant women with a non-reactive fetal non-stress test (NST) increases the conversion rate to a reactive NST within 20 minutes, compared to observation with a sugar-free white chocolate placebo. A total of 190 singleton pregnant women at 36-41 weeks gestation with a non-reactive NST will be recruited at the Hospital General San Felipe, Tegucigalpa, Honduras. Participants will be randomly assigned to either the intervention group (dark chocolate) or the control group (placebo). The primary outcome is the proportion of NSTs that become reactive. Secondary outcomes include changes in specific cardiotocographic parameters, total monitoring time, need for additional tests, and maternal satisfaction.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Singleton pregnancy between 36+0 and 41+6 weeks of gestation. * Baseline Non-Stress Test (NST) classified as non-reactive after a standard 20-minute recording (absence of โ‰ฅ2 accelerations of โ‰ฅ15 beats per minute lasting โ‰ฅ15 seconds). * Intact amniotic membranes and not in active labor (cervical dilation \<4 cm, with absent or irregular contractions). * Ability to provide written, informed consent. * Literacy: Ability to read and write (to ensure comprehension of the consent form and study materials). * Access to a telephone or electronic device for the 24-hour safety follow-up contact. Exclusion Criteria: 1. Pregnancy-related exclusions: * Multiple gestation (twins, triplets, etc.). * Known major fetal malformation. * Diagnosis of severe fetal growth restriction with abnormal umbilical artery Doppler. * Premature rupture of membranes. * Active vaginal bleeding or placenta previa with hemorrhage. * Suspected or confirmed chorioamnionitis. 2. Maternal medical exclusions: * Severe preeclampsia, eclampsia, or HELLP syndrome. * Uncontrolled severe hypertension. * Pregestational diabetes or gestational diabetes requiring insulin or other antihyperglycemic medication. * Capillary blood glucose level \>140 mg/dL at the time of screening. * Maternal fever โ‰ฅ38ยฐC or maternal tachycardia \>120 beats per minute. 3. Interference with test interpretation: * Use of sympathomimetic drugs within 12 hours prior to the study intervention. * Maternal cardiac arrhythmias. 4. Contraindications to the intervention: * Known allergy to cocoa or chocolate. * Severe caffeine intolerance. * Phenylketonuria. * Gastrointestinal conditions that would prevent oral intake (e.g., intractable vomiting, ileus, obstruction).
๐Ÿ’Š

What it tests

  • Dark Chocolate
  • Sugar-free White Chocolate
๐Ÿ“

Where

1 site
Hospital San Felipe
Tegucigalpa, Honduras
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy