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Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair

RecruitingNAAges 18 Years - anyAllSwissmed Hospital
NCT07422441 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older * Elective repair of a large ventral abdominal wall hernia (including incisional hernia) * Preoperative botulinum toxin A preparation performed as part of the local prehabilitation pathway * Preoperative abdominal CT available * General anesthesia with mechanical ventilation and feasibility of standardized intraoperative respiratory mechanics measurements Exclusion Criteria: * Severe preoperative respiratory failure judged to preclude standardized intraoperative respiratory mechanics assessment * Inability to obtain reliable static respiratory system compliance measurements at predefined timepoints * Hemodynamic instability preventing protocolized measurements (as judged by the anesthesiologist)
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What it tests

  • Compliance-Guided Abdominal Wall Closure Decision Strategy
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Where

1 site
LUX MED Hospital, Gdaล„sk
Gdansk, Poland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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