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Bone Regeneration Using PRF After Cyst Enucleation

RecruitingNAAges 18 Years - 80 YearsAllSana'a University
NCT07424716 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws. The study will assess bone healing outcomes and compare PRF application with conventional management methods.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients diagnosed with odontogenic cysts requiring surgical enucleation. * Presence of a postoperative osseous defect in the jaws after cyst enucleation. * Age ≥ 18 years. * Systemically healthy patients (ASA I or II). * Patients willing to participate and sign informed consent. Exclusion Criteria: * Patients with systemic diseases affecting bone healing (e.g., uncontrolled diabetes, osteoporosis). * Patients receiving bisphosphonates or long-term corticosteroid therapy. * Smokers (\>10 cigarettes/day). * Pregnant or lactating women. * Patients with acute infection at the surgical site. * Patients unwilling to participate or unable to attend follow-up visits.
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What it tests

  • Autologous Platelet-Rich Fibrin (PRF)
  • Conventional Surgical Management
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Where

1 site
Faculty of Medicine and Health Sciences - Sana'a University
Sanaa, Yemen
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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