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Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.

RecruitingNAAges 18 Years - 65 YearsAllRicardo Mora
NCT07426172 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance. The investigators will conduct an intervention study in which blood lactate levels will be elevated via intravenous infusion of sodium lactate. State of the art metabolic assessment using stable isotopes and indirect calorimetry will be used to study alterations in fat and carbohydrate metabolism.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men and women * \>18 years of age * Women non-pregnant or taking contraceptive medication * Physically active according to WHO's guidelines * Metabolic syndrome as IDF 2009 criteria (Alberti et al., Circulation) * Written and verbal consent to participation Exclusion Criteria: * Chronic illness that prevents them from exercising * Affected blood samples at screening, as assessed by the PI * Assessed as unsuitable by PI
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What it tests

  • hyperlactacidemia
  • Saline (0.9%, sterile, for infusion)
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Where

1 site
Facultad de Ciencias del Deporte
San Javier, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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