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Amygdala Insula Retraining in the Management of Perimenopause Symptoms

RecruitingNAAges 38 Years - 60 YearsFemaleChronic Conditions Research Fund
NCT07427459 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms. Our research questions include: Does AIR reduce overall perimenopausal symptom burden compared to a wait-list control? Does AIR improve sleep disturbance, vasomotor symptom interference, fatigue, mood, anxiety, and quality of life in perimenopausal individuals? Are symptom changes associated with improvements in autonomic regulation and sleep parameters, as reflected by exploratory wearable measures including heart rate variability?

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📋 Eligibility rules (as published)
Inclusion Criteria: * Experiencing perimenopausal symptoms * Meets STRAW+10 criteria based on self-assessment (-2 to +1c) * Able to read and understand English * Access to internet Exclusion Criteria: * Pregnancy * Presence of a severe psychiatric condition requiring immediate clinical intervention * Uncontrolled thyroid disease or prolactinoma * Active cancer treatment * Inability to provide informed consent * Any medical or psychiatric condition that, in the judgment of the investigator or study team, would interfere with safe participation or study completion
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What it tests

  • Amygdala and Insula Retraining (AIR)
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Where

1 site
Luther College Department of Psychology
Decorah, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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