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Tracking and Continuity of Care in Advanced HIV Disease

Recruitingn/aAges 18 Years - anyAllBoston University
NCT07428577 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Despite the scale-up of HIV testing and the implementation of the universal test-and-treat policy, a substantial proportion of people living with HIV (PLHIV) continue to present with advanced HIV disease (AHD), defined by a CD4 count below 200 cells/µL and/or WHO clinical staging of stage 3 or 4. Global and regional analyses estimate that nearly half of hospitalized PLHIV meet criteria for AHD, with similar findings reported in South Africa. Patients with AHD face high risks of opportunistic infections, hospitalization, and mortality, and frequently disengage from care after discharge. This study aims to examine inpatient and post-discharge care pathways for individuals with AHD in South Africa, identify gaps in continuity of care between hospitals and primary healthcare (PHC) facilities, and generate evidence to inform strategies that strengthen linkage, retention, and long-term outcome

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Known HIV positive status * Admitted to inpatient care for an AHD-related illness * Aged 18 years and above * Able to provide written consent or consent using a thumbprint * Consent to be contacted after discharge and can provide contact information Exclusion Criteria: * Confined to tuberculosis isolation ward or other wards for patients with acute infectious disease that requires isolation procedures * Not physically, mentally, or emotionally able to participate in the study prior to discharge, in the opinion of facility or study staff * Unable to communicate in any of the languages into which the questionnaire has been translated or that is known to the research assistant
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What it tests

  • Not listed
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Where

1 site
Helen Joseph Hospital
Johannesburg, South Africa
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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