Secretome vs. PRP Injections for Hair Density and Growth in Androgenetic Alopecia Patients

Inclusion Criteria: * Male patients with androgenetic alopecia, aged 25 to 59 years, with clinical presentation consistent with Hamilton-Norwood grades II to VI, seeking treatment at the Dermatology and Venereology Outpatient Clinic of Prof. Dr. I.G.N.G. Ngoerah General Hospital. * Female patients with androgenetic alopecia, aged 25 to 59 years, with clinical presentation consistent with Ludwig grades I to III, seeking treatment at the Dermatology and Venereology Outpatient Clinic of Prof. Dr. I.G.N.G. Ngoerah General Hospital. * Female patients who are not currently pregnant or breastfeeding. * Patients who have discontinued anti-androgen medication and minoxidil for at least 1 month prior to the procedure. * Patients with no known allergies to secretome components and/or materials used in the platelet-rich plasma (PRP) preparation process. * Patients who are proficient in Indonesian and willing to provide written informed consent. Exclusion Criteria: * Participants who are unable to speak or understand Indonesian and/or are unwilling to provide written informed consent. * Patients presenting with types of hair loss other than androgenetic alopecia. * Patients currently undergoing therapy with 5-alpha reductase inhibitors. * Patients who have received intradermal corticosteroid injections to the scalp within at least 6 months prior to the study. * Patients with active infections and/or active dermatitis on the scalp. * Patients with a known history of allergy to secretome components and/or materials used in the platelet-rich plasma (PRP) preparation process. * History of hypertrophic scarring or blood clotting (coagulation) disorders. * Patients unable to complete the research procedures in their entirety.