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Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA

RecruitingPhase 4Ages 18 Years - 89 YearsAllAllegheny Singer Research Institute (also known a…
NCT07430085 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective Cohort of patients who are scheduled for a Robot Assisted Total Knee Arthroplasty (RATKA). A prospective survey of patient reported outcome measures (Numeric Rating Scale) will be obtained postoperatively of 72 hours, as well as at the postoperative opioid consumption after 72 hours.

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📋 Eligibility rules (as published)
Inclusion Criteria: Males or females aged 18-89 years Diagnosed with knee osteoarthritis requiring surgical intervention Indicated for unilateral RATKA Exclusion Criteria: Pediatric, pregnant, or incarcerated patients BMI of more than 45 kg/m2 Prolonged opioid use history of \>5 mg/day for \>1 month History of contralateral TKA \<2 years prior to the index TKA Type 1 Hypersensitivity to NSAIDs or local anesthetics Diagnosis of severe renal disease
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What it tests

  • bupivacaine-meloxicam (extended release)
  • Bupivacaine
  • Ketorolac
  • Lidocaine (drug)
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Where

1 site
AHN Orthopedic Surgery Cranberry Township
Cranberry Township, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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