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← Trials
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A Study to Learn About mRNA Vaccines Against Influenza in Adults

RecruitingPhase 2Ages 18 Years - anyAllPfizer
NCT07431853 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus). This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison. Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.

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📋 Eligibility rules (as published)
Inclusion Criteria • Healthy and medically stable participants who are determined by medical history, physical examination (if clinically required), and clinical judgment of the investigator to be eligible for inclusion in the study. Exclusion Criteria * Tested positive for influenza ≤5 months (150 days) prior to Visit 1 (Day 1). * Vaccination with any investigational or licensed influenza vaccine ≤5 months (150 days) before Visit 1 (Day 1). * Receipt of antiviral therapies for influenza (eg, Tamiflu) ≤5 months (150 days) prior to Visit 1 (Day 1).
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What it tests

  • Vaccine Candidate #1
  • Vaccine Candidate #2
  • Vaccine Candidate #3
  • Vaccine Candidate #4
  • Vaccine Candidate #5
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Where

15 sites
AMR Clinical
Mobile, United States
Diablo Clinical Research, LLC d/b/a Flourish Research
Walnut Creek, United States
Clinical Research Consulting, LLC
Milford, United States
George Washington Medical Faculty Associates
Washington D.C., United States
Indago Research & Health Center, Inc
Hialeah, United States
Palm Springs Community Health Center
Miami Lakes, United States
Clinical Research Atlanta
Stockbridge, United States
East-West Medical Research Institute
Honolulu, United States

…and 7 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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