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Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic

Recruitingn/aAges 65 Years - anyAllTomas Bata Hospital, Czech Republic
NCT07432009 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total hip arthroplasty in the Czech Republic. Postoperative delirium is a frequent and serious neurocognitive complication in senior surgical patients and is associated with increased morbidity, mortality, prolonged hospitalization, and impaired functional and cognitive outcomes. Despite international recommendations, routine preoperative cognitive screening remains insufficiently implemented. The study evaluates the predictive value of the ALBA test, a brief cognitive screening tool, performed during the pre-anesthetic assessment. Postoperative delirium will be assessed using the validated CAM-ICU instrument for up to 72 hours after surgery. Secondary objectives inclu

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 65 years * Elective total hip arthroplasty in general or regional anesthesia * ASA physical status I-III * Ability to understand and cooperate during testing; no severe sensory impairment (compensatory aids allowed) * Expected postoperative hospitalization in ICU, PACU, or standard ward Exclusion Criteria: * Glasgow Coma Scale ≤ 14 * Limited legal capacity * Active psychiatric disorder (e.g., psychotic disorder, bipolar disorder) * Active oncological disease * Chronic use of strong opioids * Premedication with anxiolytics or antipsychotics during preanesthetic evaluation * Acute reoperation within 3 months of primary surgery * Refusal to participate or withdrawal of consent
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What it tests

  • Not listed
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Where

7 sites
University Hospital Brno - Bohunice
Brno, Czechia
University Hospital Olomouc - Department of Anaesthesiology, Resuscitation and Intensive Care
Olomouc, Czechia
University Hospital Ostrava - Department of Anaesthesiology, Resuscitation and Intensive Care
Ostrava, Czechia
University Hospital Královské Vinohrady
Prague, Czechia
University Hospital Motol
Prague, Czechia
Vsetín Hospital
Vsetín, Czechia
Tomas Bata Regional Hospital
Zlín, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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