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Exercise Timing and Postprandial Glucose Responses

RecruitingNAAges 18 Years - 35 YearsAllTechnical University of Munich
NCT07434349 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This interventional crossover study examines the effect of exercise timing relative to meal intake on postprandial glucose responses in healthy, physically active young adults. Participants complete five experimental conditions involving endurance exercise performed before or after breakfast or dinner, as well as a non-exercise control condition, while wearing a continuous glucose monitoring device. Postprandial glucose responses are assessed for the three consecutive meals following each exercise session. Following morning exercise, outcomes are assessed after breakfast, lunch, and dinner on the same day. Following evening exercise, outcomes are assessed after dinner on the same day and after breakfast and lunch on the subsequent day. All meals are standardized and consumed at fixed clock times.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 to 35 years * Body mass index 18.5 to 24.9 kg per square meter * Able to complete 45 minutes of continuous running at an intensity corresponding to 75 to 85 percent of maximal heart rate without stopping * Engages in regular endurance-type physical activity * Habitual waking times are compatible with the fixed breakfast time of 08:00 * Willing and able to comply with all study procedures, including standardized meals, exercise sessions, behavioral restrictions, and continuous glucose monitoring * For female participants: non-pregnant and using stable hormonal contraception for at least 3 months Exclusion Criteria: * Acute or chronic illness * Metabolic disorders or conditions associated with altered glucose or lipid metabolism * Use of medications known to interfere with glucose metabolism or study outcomes * Intolerance or allergy to components of the standardized study diets * Pregnancy or breastfeeding * Body mass index greater than or equal to 25 kg per square meter * Current or past eating disorder, or any medical condition or medication that could affect appetite regulation, glucose regulation, or make vigorous endurance exercise unsafe * Current smoking or use of nicotine-containing products
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What it tests

  • Timed Endurance Exercise
  • No Exercise Control
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Where

1 site
Technical University of Munich
München, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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