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Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)

Recruitingn/aAges 18 Years - anyAllJosip Juraj Strossmayer University of Osijek
NCT07437729 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary research objective of the project is to determine the role of eGC in microvascular reactivity in CKD (cross-sectional study 1). The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CKD, as well as identify new biomarkers for CKD.

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients with CKD of hypertensive etiology (grades 1-2 and 3-5; eGFR CKD-EPI GFR ≥ 90 ml/min/1.73 m², i.e. \< 60 mL/min/1.73 m2), non-diabetics, non-smokers * patients with hypertension (according to ESH2023 Guidelines) without kidney damage (eGFR CKD-EPI \>90 mL/min/1.73 m2) non-diabetics, non-smokers * healthy volunteer subjects as controls Exclusion Criteria: * kidney disease of any other etiology except hypertension * endocrine, autoimmune or inflammatory diseases that could affect kidney function. * smoking * diabetes
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What it tests

  • Not listed
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Where

1 site
Osijek University Hospital
Osijek, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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