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AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation

Recruitingn/aAges 22 Years - anyAllAiatella Oy
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In plain words

What the trial is, and whether it could suit you

This study will test how well an artificial intelligence (AI) software called Aorta AIM measures the size of the aorta (the body's main blood vessel) from CT scans. The aorta can become enlarged over time, which may lead to serious health problems. Doctors need to measure the aorta accurately to monitor patients and decide on treatment. Currently, doctors measure the aorta manually on CT scans, which takes time and can vary between different doctors. Aorta AIM is designed to measure the aorta automatically and consistently. In this study, researchers will compare Aorta AIM's measurements to those made by experienced radiologists or cardiologists (doctors who specialize in reading medical images). The study will use CT scans that have already been taken as part of routine medical care - no additional scans or procedures are needed. The study will include approximately 250 participants

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
* Adults โ‰ฅ22 years at time of imaging * Studies performed 1 Jan 2016 - 31 August 2025 * CT imaging of the whole, thoracic, or abdominal aorta, with or without contrast enhancement, acquired with any gating protocol (including non-gated) * Slice thickness โ‰ค 3mm * CT imaging in which truncation creates discontinuity within a targeted aortic region, preventing reliable diameter measurement (e.g., cardiac-focused CT acquisitions where an incomplete or absent aortic arch creates discontinuity between the aortic root and the descending thoracic aorta) o Partial aortic coverage is not grounds for exclusion. Where truncation affects individual regions, only those specific regions will be excluded from analysis; remaining fully captured regions will be retained for measurement. * Metal implants \<5cm from aorta (e.g. thoracic stent) * Prior aortic surgery * Severe motion artifacts (e.g. \>3mm vessel blurring) * Congenital aortic anomalies (e.g. coarctation, vascular rings) * Post-traumatic aortic repairs * The patient opted out of having their data used for medical research before the date of cross-referencing by the site team
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What it tests

  • Aorta AIM Automated Measurement
  • Expert Radiologist Manual Measurement
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Where

3 sites
University of North Carolina at Chapel Hill
Chapel Hill, United States
Innovation Health Services
Norfolk, United States
Hospital Israelita Albert Einstein
Sรฃo Paulo, Brazil
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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