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Comparison of Root Canal Desinfection Protocols

RecruitingNAAges 18 Years - 70 YearsAllState University of New York at Buffalo
NCT07439614 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients able to give informed consent and willing/able to comply with study procedures and follow-up. * Molar teeth indicated for endodontic treatment. * Teeth with intact pulp-chamber walls (no extensive coronal destruction). * Necrotic pulp confirmed by pulp testing. * Clinical and radiographic evidence of asymptomatic apical periodontitis. Exclusion Criteria: * Immature teeth * Teeth with calcified or obliterated canals * Teeth with extensive coronal destruction * Teeth with previous endodontic treatment * Symptomatic apical periodontitis * Teeth with periodontal pockets greater than 4 mm * Patients who have received systemic antibiotics in the last 3 months * Patients with a history of diabetes or immune impairment * Pregnant patients
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What it tests

  • Desinfection device
  • Analytical microbiological methods
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Where

1 site
Advance Education in Endodontics Program
Buffalo, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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