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Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease

Recruitingn/aAges 18 Years - anyAllSakarya University
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In plain words

What the trial is, and whether it could suit you

This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD). Sarcopenia is commonly assessed using computed tomography (CT)-based skeletal muscle area measurements at the L3 vertebral level, which are considered a gold standard method. However, CT is not always feasible due to radiation exposure and accessibility limitations. In this study, muscle strength will be assessed using handgrip dynamometry, and muscle mass will be evaluated using ultrasonography of selected skeletal muscles. In patients with available recent abdominal CT imaging, L3 skeletal muscle area will be recorded. The primary objective is to compare ultrasonographic muscle measurements with CT-based assessments and to evaluate the agreement between these methods. This study aims to determine whether ultrasonography can serv

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Established diagnosis of inflammatory bowel disease (ICD-10: K50.\* Crohn's disease, K51.\* ulcerative colitis) * Ability to provide written informed consent * Ability to undergo ultrasonographic muscle assessment and handgrip strength testing * Availability of an abdominal computed tomography (CT) scan performed within the previous 6 months Exclusion Criteria: * Known neuromuscular disorders or primary muscle diseases * Major orthopedic conditions affecting muscle strength assessment * Pregnancy * Abdominal wall defects or conditions interfering with ultrasound assessment * Incomplete clinical or imaging data * Any condition preventing reliable ultrasound or handgrip measurement
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What it tests

  • Muscle Ultrasonography
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Where

1 site
Sakarya University Faculty of Medicine, Training and Research Hospital
Sakarya, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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