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Frailty and Outcomes in Older Emergency Department Patients With Pneumonia

Recruitingn/aAges 65 Years - anyAllEge University
NCT07442656 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on acute physiological derangements and may not adequately capture biological reserve and frailty in older adults. Frailty is a geriatric syndrome reflecting increased vulnerability to stressors and reduced recovery capacity. This prospective observational cohort study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS) for in-hospital mortality, 30-day mortality, and morbidity in patients aged 65 years and older presenting to the emergency department with pneumonia. Additionally, the study will assess whether incorporating frailty assessment into existing pneumonia severity scores improves prognostic accuracy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥65 years * Clinical and radiological diagnosis of pneumonia in the emergency department * Ability to obtain informed consent from the patient or legal representative * Availability of a caregiver or relative able to describe baseline functional status Exclusion Criteria: * Presentation with cardiopulmonary arrest or ongoing cardiopulmonary resuscitation at admission * Confirmed COVID-19 pneumonia * Inability to obtain reliable baseline functional history due to absence of an informant * Refusal to provide informed consent
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What it tests

  • Clinical frailty scale
  • Clinical Frailty Scale (CFS)
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Where

1 site
Özge Can
Izmir, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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