🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)

Recruitingn/aAges 18 Years - 85 YearsAllUrbano Santana Penin
NCT07445516 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial. Conservative therapies-including no active intervention-often alleviate symptoms; however, approximately 3% of the population develops persistent forms associated with substantial individual suffering and significant social and economic burden. At the Unit of Occlusion and Prosthodontics of the University of Santiago de Compostela (USC), Physiologically Oriented Occlusal Equilibration (POOE) has been used for chronic painful TMDs since 1985. POOE aims to correct unilateral mastication patterns and to establish appropriate non-working side contacts in order to protect the temporomandibular joints from mechanical overload. Singh (Cochrane, 2024) emphasized that oc

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Previous occlusal equilibration for TMD pain at the University of Santiago. * Be diagnosed with joint and/or muscle TMD pain according to DC/TMD. * Be aged 18-85 years. * Be completely dentate with normal or adequately restored occlusion (fixed crowns/bridges allowed). * Report pretreatment significant TMD pain (VAS/NRS 4-9 on a 0-10 scale). * Have actively sought treatment and been referred to the University/Hospital service. * Have undergone ≥6 months of prior conservative therapy. Exclusion Criteria: * Psychosis, major depression, substance abuse, or cognitive impairment. * Opioid (morphine-derivative) addiction. * Ongoing litigation or disability claims related to chronic pain. * Dental professional background. * Orthodontic treatment within the last 2 years. * Severe tooth mobility (grade 3). * Other pain conditions indistinguishable from or more severe than TMD pain. * Additionally, patients will be excluded if minimally invasive occlusal adjustment cannot achieve equilibration, defined by: 2 mm discrepancy between maximal intercuspation and centric occlusion, and/or 4 mm total interarch discrepancy (≥2 mm on one side) in defined premolar/molars reference points, measured intraorally using a Boley gauge.
💊

What it tests

  • Not listed
📍

Where

2 sites
Universidad de Santiago de Compostela
Santiago de Compostela, Spain
Urbano Santana Penín
Santiago de Compostela, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy