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Effect of a High-Protein, High-Fiber Pre-Fast Meal on Satiety and Glycemic Profiles During Fasting

RecruitingNAAges 18 Years - anyAllKing Faisal University
NCT07447505 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized crossover study investigates the effect of consuming a high-protein, high-fiber pre-fast meal on subjective satiety and glycemic responses during fasting hours in healthy adults. Participants will complete two dietary conditions in a randomized order: a standardized high-protein, high-fiber pre-fast meal and a low-protein, low-fiber pre-fast meal guided by dietary instructions. Each condition will be followed for two consecutive days and separated by a three-day washout period. Outcomes include subjective appetite sensations during fasting hours, glycemic profiles assessed using continuous glucose monitoring (CGM), and exploratory analyses examining the association between glucose dynamics and appetite sensations.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years and older * Willingness to comply with study procedures, including fasting and continuous glucose monitoring * Ability to provide informed consent Exclusion Criteria: * Diagnosed diabetes mellitus or known metabolic disease * History of cardiovascular, gastrointestinal, or endocrine disorders that may affect study outcomes * Use of medications known to affect glucose metabolism or appetite * Pregnancy or lactation * Known allergy or intolerance to any study meal components (oats, dairy, peanuts, nuts, cranberries)
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What it tests

  • High-Protein, High-Fiber Meal
  • Low-Protein, Low-Fiber Meal
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Where

1 site
King Faisal University
Al-Ahsa, Saudi Arabia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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