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← Trials
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Losartan for Corneal Fibrosis

RecruitingNAAges 18 Years - anyAllUniversidad Autonoma de Nuevo Leon
NCT07449000 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective, randomized, double-blinded, controlled clinical trial designed to evaluate the efficacy and safety of topical losartan in improving visual acuity, contrast sensitivity and reducing corneal densitometry, corneal aberrations and corneal scarring severity in adult patients with corneal scars of different etiologies. Participants will be randomly assigned to receive either topical losartan 0.8 mg/mL or placebo eyedrops 6 times per day for six months.

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📋 Eligibility rules (as published)
* Inclusion Criteria: * Adults aged 18 years or older * Presence of corneal scar with a duration of at least 1 month * Corneal scars of any etiology * Corneal scars with or without corneal neovascularization * Stable corneal scar without epithelial defect * No active treatment for the underlying condition for at least 1 month * Exclusion Criteria: * Refusal or inability to provide written informed consent * Presence of corneal epithelial defect or friable epithelium * Age under 18 years * Pregnancy * Known allergy or hypersensitivity to losartan
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What it tests

  • Topical losartan
  • Placebo Control
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Where

1 site
Ophthalmology Department
Monterrey, Mexico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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