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Low Dose Epcoritamab Plus GemOx in R/R DLBCL

RecruitingPhase 2Ages 18 Years - 65 YearsAllHospital Universitario Dr. Jose E. Gonzalez
NCT07451652 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this study, researchers are looking to determine whether Gemcitabine/Oxaliplatin plus a lower dose of Epcoritamab (12 mg) works to treat subjects with relapsed/refractory diffuse large B-cell lymphoma, who are candidates to autologous stem cell transplantation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects with relapsed/refractory diffuse large B-cell lymphoma who have received at least 1 previous line of treatment and that are candidates to autologous stem cell transplant * ECOG 0-2 * Women of reproductive age who agree on getting a contraceptive method * Subjects who fulfill Lugano´s criteria for disease activity * Subjects who voluntarily accept to participate in this study Exclusion Criteria: * Active bacterial, viral or fungal infection * Subjects who have already received an autologous o allogeneic stem cell transplantation * Subjects with other active neoplasias * Subjects with end-stage failure
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What it tests

  • Epcoritamab
  • Gemcitabine (1000 mg/m2)
  • Oxaliplatin
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Where

1 site
Hospital Universitario "Dr. José Eleuterio González"
Monterrey, Mexico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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