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Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)

Recruitingn/aAges 18 Years - anyAllJosip Juraj Strossmayer University of Osijek
NCT07451873 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary research objective of the project is to determine the role of eGC in microvascular reactivity in patients with coronary heart disease (CHD) before and after bypass grafting (cross-sectional study 2).The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CVD, as well as identify new biomarkers for CVD.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult patients of both sexes over 18 years of age * Caucasian * undergoing elective coronary artery bypass grafting (CABG) * provided written informed consent Exclusion Criteria: * emergency surgery * sepsis or severe systemic inflammation before surgery * severe renal or hepatic insufficiency * immunosuppression * serious comorbidities (e.g., active cancer) * therapies that could affect oxidative stress (e.g., high doses of corticosteroids)
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What it tests

  • Not listed
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Where

1 site
Osijek University Hospital
Osijek, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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