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Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery

Recruitingn/aAges 18 Years - 80 YearsAllBursa Yuksek Ihtisas Training and Research Hospit…
NCT07452367 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Bentall surgery is a major cardiac procedure involving replacement of the ascending aorta, aortic root, and aortic valve, typically requiring cardiopulmonary bypass (CPB) and sometimes deep hypothermic circulatory arrest (DHCA). Due to its complexity, it carries a significant risk of postoperative neurological complications including stroke and postoperative cognitive dysfunction (POCD). This prospective observational study aims to evaluate the relationship between perioperative bilateral optic nerve sheath diameter (ONSD) measurements obtained by ultrasound and postoperative cognitive functions in patients undergoing elective Bentall surgery. ONSD is a non-invasive surrogate marker of intracranial pressure that can be measured at the bedside using ultrasound. In addition to routine hemodynamic monitoring and cerebral oximetry (NIRS), bilateral ONSD will be measured at predefined intra

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 80 years * Scheduled for elective Bentall procedure * Requiring cardiopulmonary bypass (CPB) * Willing to participate and able to provide informed consent * Able to complete the MoCA cognitive assessment test Exclusion Criteria: * Age below 18 or above 80 years * Emergency Bentall surgery * Pre-existing diagnosed cognitive impairment or dementia * History of prior stroke or neurological disease * Significant carotid artery stenosis * Inability to complete the MoCA test (language barrier, illiteracy, visual or hearing impairment) * Refusal to participate or inability to provide informed consent * Patients with known psychiatric disorders * Reoperation (redo surgery) * Patients with severe renal or hepatic failure
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What it tests

  • Not listed
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Where

1 site
Bursa High Specialization Training and Research Hospital
Bursa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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