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Comparison of the Efficacy of Combined Transversus Thoracic Plane Block and Serratus Anterior Plane Block Versus Erector Spinae Plane Block in the Management of Sternotomy Pain

RecruitingNAAges 18 Years - 80 YearsAllUludag University
NCT07452627 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background and Purpose: Median sternotomy is the standard surgical approach for cardiac procedures, yet it is associated with significant postoperative pain. Inadequate pain management can lead to pulmonary complications and chronic pain syndromes. While opioids are a cornerstone of multimodal analgesia, their side effects-such as sedation, respiratory depression, and nausea-can delay recovery. Furthermore, neuraxial techniques like epidural analgesia are often avoided in cardiac surgery due to the risks associated with systemic heparinization. This study aims to compare the efficacy of two non-neuraxial regional anesthesia techniques: the combination of Transversus Thoracic Plane Block (TTPB) and Serratus Anterior Plane Block (SAPB) versus the Erector Spinae Plane Block (ESPB). Study Design and Population: This prospective, randomized study includes 50 patients (ASA I-III, aged 18-80)

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged between 18 and 80 years. * Patients with American Society of Anesthesiologists (ASA) physical status I, II, or III. * Patients who provide written informed consent. * Patients scheduled for cardiac surgery via elective sternotomy. Exclusion Criteria: * Pregnancy or suspected pregnancy * Body Mass Index (BMI) \> 35 kg/m² * History of allergy to local anesthetics or opioids * Suspected coagulopathy or infection at the injection site * Severe neurological, psychiatric, hepatic, or renal failure
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What it tests

  • TTP Block
  • ESP Block
  • SAP Block
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Where

1 site
Bursa Uludag University Hospital
Bursa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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