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Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction

RecruitingNAAges 13 Years - 20 YearsAllAl-Azhar University
NCT07455656 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial

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📋 Eligibility rules (as published)
Inclusion criteria: 1. Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion). 2. Fully erupted permanent teeth (except third molar). 3. Age 13-20 patients. 4. No previous orthodontic treatment. 5. Good oral and general health. 6. No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement. Exclusion criteria: 1. Patients with impacted canines. 2. Patients with severe crowding. 3. Patients with untreated decay or any endodontic lesions. 4. Patients with thyroid, parathyroid, or renal and liver disease.
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What it tests

  • patients will receive local application of vitamin D3 combined with corticision
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Where

1 site
Orthodontic Outpatient Clinic, Faculty of Dental Medicine, Al-Azhar University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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