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Healthy Expectancy Through Routine Antenatal STI Screening

RecruitingNAAges 15 Years - anyFemaleAdriane Wynn
NCT07458802 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will evaluate whether routine screening and treatment for two common sexually transmitted infections, chlamydia and gonorrhoea, during pregnancy can reduce preterm birth and other poor birth outcomes in Botswana, and whether this approach is affordable and cost-effective for the health system. About 2,000 pregnant women attending their first antenatal care visit at up to 10 government clinics in Botswana will be invited to join the study. All women will first receive the usual antenatal care services provided in Botswana, including routine health checks and HIV and syphilis testing. Women who enroll in the study will be randomly assigned to one of two groups: 1. Standard of care group: Women receive routine antenatal care only. 2. Intervention group: In addition to routine antenatal care, women are screened for chlamydia and gonorrhoea using self-collected vaginal swabs at t

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Asymptomatic for cervicovaginitis at first ANC (i.e., not syndromically treated for an STI by clinic midwives at first ANC) 2. Age ≥ 15 years 3. Currently pregnant 4. ≤20 weeks gestation (based on gestational age in obstetric record or last menstrual period if gestational age missing from record) 5. Attending first ANC visit 6. Residence in Gaborone, Bostwana or surrounding villages through the time of delivery 7. Mentally competent to understand study procedures or give informed consent
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What it tests

  • Chlamydia trachomatis and Neisseria gonorrhoeae screening
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Where

1 site
Botswana Harvard Health Partnership
Gaborone, Botswana
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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