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Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use

Recruitingn/aAges 18 Years - 65 YearsMaleElazığ Mental Health and Diseases Hospital
NCT07459270 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU). Participants hospitalized at Elazığ Mental Health and Diseases Hospital who meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for MP will be included. Participants will be divided into two groups based on the presence or absence of LCU. Psychiatric symptoms and clinical characteristics will be assessed weekly during an eight-week inpatient follow-up period using standardized psychometric instruments. The study aims to determine whether LCU influences the course and severity of psychiatric symptoms in MP and to identify environmental, individual, and familial factors associated with symptom progression.

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📋 Eligibility rules (as published)
1. For Methamphetamine-Induced Psychotic Disorder plus Lifetime Cannabis Use (MP + LCU) Group: \*Inclusion Criteria: • Diagnosis of MP according to DSM-5-TR * Diagnosis of Cannabis Use Disorder according to DSM-5-TR * Medication-free for at least one month prior to admission * Age ≥ 18 years and \<65 years * Provided informed consent For Methamphetamine-Induced Psychotic Disorder plus Lifetime Cannabis Use (MP + LCU) Group: \*Exclusion Criteria: • Hypertension • Diabetes mellitus • Chronic kidney disease • Rheumatoid arthritis • Systemic lupus erythematosus • Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than MP * Alcohol use disorder 2. For Methamphetamine-Induced Psychotic Disorder (MP without LCU) Group: \*Inclusion Criteria: • Diagnosis of MP according to DSM-5-TR • Medication-free for at least one month prior to admission • Age ≥ 18 years and \<65 years • Provided informed consent For Methamphetamine-Induced Psychotic Disorder (MP without LCU) Group: \*Exclusion Criteria: • Hypertension • Diabetes mellitus • Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than MP * Alcohol use disorder
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What it tests

  • Not listed
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Where

2 sites
Elazığ Mental Health and Diseases Hospital
Elâzığ, Turkey (Türkiye)
Elazığ Mental Health and Diseases Hospital
Elâzığ, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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