🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

RecruitingNAAges 18 Years - 50 YearsAllBoston University Charles River Campus
NCT07459803 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an individuals own voice and the movements of their speech muscles, and a motor system that builds and reads out learned motor patterns. The investigators are studying how these systems work together and how they differ across individuals. Investigators will test 90 adults between 18 and 50 years old, including people who stutter, people with dyslexia, and people with typical speech and reading development. Participants will complete several short speech tasks in which the sounds they hear or the movements of their jaw or larynx are briefly changed. These responses will be used to measure each person's speech motor skills and to estimate the settings of a computer model call

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Native speakers of American English * Adults age 18-50 * Age-appropriate cognitive and receptive vocabulary skills * Age-appropriate hearing * Adults with dyslexia will have a history of dyslexia or report of ongoing reading difficulties that will be confirmed at the first screening visit * Adults who stutter will have a history of stuttering that will be confirmed at the first screening visit Exclusion Criteria: * History of neurological disorder, including a history of seizures * Major brain injury, brain surgery, or stroke * Orthodontia or atypical oral structure (e.g., cleft palate) that interferes with speech * Fluency disorder (except those in the persons who stutter cohort), apraxia of speech, or dysarthria * Language or reading disorder (except those in persons with dyslexia cohort) * Standardized score below 80 on the Kaufman Brief Intelligence Test * Standardized score below 1 standard deviation on the NIH Toolbox Picture Vocabulary Test * Pregnancy * Severe claustrophobia * Presence of magnetically or mechanically active implant, or other ferromagnetic material embedded in any part of the body * Significant scalp lesions that would prevent transcranial direct stimulation
💊

What it tests

  • Unpredictable auditory feedback perturbation: 2 behavioral sessions
  • Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions
  • Sustained F1 auditory feedback perturbation
  • Sustained F0 auditory feedback perturbation
  • Reflexive somatosensory perturbation
📍

Where

2 sites
Boston University Charles River Campus
Boston, United States
Boston University
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy