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Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection

RecruitingNAAges 18 Years - anyAllNorthern Jiangsu People's Hospital
NCT07462091 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. A clinical, radiological or histologic diagnosis of cirrhosis of any etiology 2. Splenomegaly with secondary hypersplenism 3. Bleeding portal hypertension 4. No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT 5. Informed consent to participate in the study Exclusion Criteria: 1. Delayed gastric emptying 2. Diarrhea 3. Hepatocellular carcinoma or any other malignancy, 4. Hypercoagulable state other than the liver disease related 5. DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs. 6. Child - Pugh C 7. Recent peptic ulcer disease 8. History of Hemorrhagic stroke 9. Pregnancy. 10. Uncontrolled Hypertension 11. Human immunodeficiency virus (HIV) infection
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What it tests

  • Vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection
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Where

2 sites
Clinical Medical College of Yangzhou University
Yangzhou, China
Clinical Medical College, Yangzhou University
Yangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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