🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards

RecruitingNAAges 18 Years - anyAllUniversitat Internacional de Catalunya
NCT07464197 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without reservoirs. Adult participants with good general and oral health and a baseline tooth shade of A2 or darker undergo bleaching with 10% carbamide peroxide. Outcomes include tooth color change (subjective and spectrophotometric measures), tooth sensitivity, gingival irritation, patient comfort, and patient satisfaction over time.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years or older * Good general and oral health * No current medical treatment (self-reported) * No need for surgical, endodontic, periodontal, or restorative dental treatment * At least six upper and six lower anterior teeth free of caries and restorations * Maxillary central incisors with baseline shade A2 or darker * Willingness to follow the study protocol and use the study-provided oral hygiene products/instructions Exclusion Criteria: * Previous tooth bleaching treatment * Orthodontic appliances or prostheses that interfere with treatment * Severe intrinsic discoloration (e.g., tetracycline staining, fluorosis, or endodontically treated teeth with discoloration) * Pregnancy or lactation * Bruxism * Gingival recession, dentin exposure, visible enamel cracks, or other conditions associated with increased sensitivity * Use of anti-inflammatory or analgesic medication during the study period (according to protocol)
💊

What it tests

  • Customized bleaching tray fabrication
  • Reservoir tray design
  • Carbamide peroxide 10%
📍

Where

1 site
Clínica Universitària d'Odontologia UIC Barcelona
Sant Cugat del Vallès, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy