🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple Sclerosis

Recruitingn/aAges 18 Years - anyAllMarmara University
NCT07466823 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Multiple sclerosis (MS) is a chronic neurological disease frequently associated with spasticity, which may lead to functional limitations and reduced quality of life. Although spasticity is common in MS, detailed descriptions of upper and lower extremity spasticity patterns are limited. A better understanding of spasticity patterns may help improve individualized rehabilitation and treatment planning. The aim of this study is to classify upper and lower extremity spasticity patterns in patients with multiple sclerosis and to investigate their association with quality of life. Adult patients with MS and clinical spasticity will be recruited from a tertiary care outpatient clinic. Spasticity will be evaluated using the Modified Ashworth Scale, and extremity postures will be recorded to define spasticity patterns. Functional performance will be assessed using the Timed 25-Foot Walk Test an

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of multiple sclerosis according to the 2024 McDonald criteria * Age ≥ 18 years * Presence of clinical spasticity defined as Modified Ashworth Scale score ≥ 1 in at least one joint * Ability to understand study procedures and provide informed consent * Absence of significant cognitive impairment Exclusion Criteria: * Presence of orthopedic, rheumatologic, or neurological conditions affecting movement other than multiple sclerosis * Botulinum toxin type A injection within the previous 3 months * Previous surgical treatment for upper extremity spasticity * Bone deformities affecting the upper extremity * Inability or unwillingness to provide informed consent * Presence of cognitive impairment
💊

What it tests

  • Observational Assessment
📍

Where

1 site
Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy