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Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis

RecruitingNAAges 18 Years - anyAllSt. Anne's University Hospital Brno, Czech Republ…
NCT07466966 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients diagnosed with peri-implantitis. The study investigates clinical outcomes, radiographic bone levels, patient-reported outcomes, and treatment time over 12 months.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 * Peri-implantitis diagnosis (PPD \>6 mm, BOP+, bone loss ≥3 mm) * Accessible implant surface without removing suprastructure * FMPS \<30%, FMBS \<30-35% Exclusion Criteria: * Antibiotics in last 3 months * Pregnancy/lactation * Uncontrolled diabetes (HbA1c ≥7) * Long-term SPIC (\>2 years) * Previous implant therapy \<12 months * Smoking/vaping in last 12 months * Hopeless implant * Need for adjunctive antibiotics
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What it tests

  • Non-Surgical Peri-implant Therapy (NSPT)
  • Minimally-Invasive Non-Surgical Therapy (MINST)
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Where

1 site
Syndenta s.r.o., Hlinky 92, 603 00 Brno, Czech Republic
Brno, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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