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Comparison of Transcutaneous and Blood CO₂ Measurement in Critically Ill Children

Recruitingn/aAges 1 Year - 18 YearsAllBrno University Hospital
NCT07468006 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Transcutaneous capnometry (tPCO₂) is a non-invasive method for continuous monitoring of ventilation status. In pediatric intensive care patients, it may reduce the need for repeated arterial or arterialized blood sampling. However, the accuracy of tPCO₂ may be influenced by factors such as peripheral perfusion, skin temperature, and vasopressor therapy. This prospective observational study compares transcutaneous carbon dioxide measurements with arterialized or arterial blood gas PaCO₂ values in children with respiratory insufficiency, including a subgroup receiving vasopressor support.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 1-18 years * Diagnosis of respiratory insufficiency or impaired peripheral perfusion * Expected need for more than one arterialized capillary or arterial blood gas sample * Admission to PICU Exclusion Criteria: * Repeated failure of sensor adhesion * Hypothermia \< 35 °C * Time difference \> ±5 minutes between tPCO₂ and blood sampling * Large tPCO₂ variability (\> ±1 kPa) in 15 minutes preceding blood sampling * Non-physiological tPCO₂ values incompatible with life
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What it tests

  • Not listed
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Where

1 site
University Hospital Brno
Brno, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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