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Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy

RecruitingNAAges 18 Years - 65 YearsAllSecond Affiliated Hospital, Zhejiang University, …
NCT07470021 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a procedure often performed in day-case settings but associated with significant early postoperative pain and frequent opioid use. The study evaluates whether these nerve blocks can reduce early postoperative pain-measured by the highest NRS score within 24 hours-and examines their impact on functional recovery, including motor strength and ambulation. All patients receive standardized general anesthesia and multimodal analgesia, with outcomes including opioid consumption, ankle weakness, patient satisfaction, range of motion, muscle strength, hospital stay duration, and analgesia-related costs.

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📋 Eligibility rules (as published)
Inclusion Criteria: Age between 18 and 65 years ASA physical status classification I-II Scheduled to undergo ankle arthroscopy under general anesthesia Expected to be available for follow-up on the day of surgery (day-case or short-stay surgery) Able to understand the procedures and methods of the clinical trial and voluntarily provide written informed consent Body mass index (BMI) between 16 and 32 kg/m² Exclusion Criteria: History of severe ankle nerve injury or peripheral neuropathy Severe cardiac, pulmonary, hepatic, or renal dysfunction Chronic pain or regular use of opioid analgesics for more than 3 months History of extensive ankle or lower leg surgery that may affect nerve localization Psychiatric disorders or cognitive impairment that preclude accurate NRS pain scoring Pregnancy or breastfeeding Known allergy or contraindication to any of the study drugs Any other condition deemed unsuitable for inclusion by the investigators
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What it tests

  • Ultrasound-guided popliteal sciatic and saphenous nerve block
  • Placebo nerve block
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Where

1 site
The Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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