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An Analysis of Healthy Caucasian Knees

RecruitingNAAges 20 Years - 35 YearsAllUniversitaire Ziekenhuizen KU Leuven
NCT07470671 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In current literature, databases of healthy knee anatomy and function are confined to small sample sizes or singular imaging modalities. In this study, the investigator propose constructing a unique and large-scale database of healthy Caucasian knee anatomy and function by utilizing a combination of ultra-high resolution capabilities from photon-counting CT, lower limb weightbearing orthogonal imaging (EOS) of full leg, and non-invasive ultrasound-based functional testing of the knee. This study is a collaborative effort between the orthopaedics, radiology and biomechanical engineering departments in which the same prospectively acquired database will be used for multiple independent research questions.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 20-35 years old. * 'Caucasian': 1. Self-identification as Caucasian or of European descent. 2. Self-identification as having 'fair' skin tone. 3. Both parents and all grandparents are of Caucasian or European descent. * Healthy knee and lower limb: 1. No bony orthopaedic or trauma history in the lower limb (pelvis - foot). 2. No ligamentary or soft tissue trauma history in the knee. 3. No ligamentary or soft tissue trauma in the lower limb requiring cast immobilization. Exclusion Criteria: * Individuals identifying with a race or ethnicity other than Caucasian or European descent. * Participants with known mixed racial or ethnic backgrounds that include non-Caucasian ancestry. * Participant uncertainty of pregnancy status. * Open wounds over the knee joint.
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What it tests

  • CT scan images of the knee
  • EOS scan of full leg
  • Ultrasound-based gap analysis
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Where

1 site
Universitaire Ziekenhuizen KU Leuven
Leuven, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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