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Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser

RecruitingPhase 2Ages 18 Years - 50 YearsAllMisr University for Science and Technology
NCT07472192 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone and polydeoxyribonucleotide (PDRN) combined with CO₂ laser therapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age Limitations: Participants must be between 18 and 50 years of age. * Recently cut wounds or surgical scars from about (1-6 months). * Consent to Participate: Willingness to provide informed consent and engage in all aspects of the study. Exclusion Criteria: * Pregnancy or breastfeeding at the time of study. * Known allergy to PDRN. * Medication use that could affect wound healing or inflammation, such as: * Isotretinoin. * Anticancer drugs. * High-dose corticosteroids. * Anticoagulants. * Uncontrolled medical diseases (e.g., unstable diabetes, cardiac conditions).
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What it tests

  • Polydeoxyribonucleotide
  • Fractional CO2 laser assisted PDT
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Where

1 site
Misr University for Science and Technology
Giza, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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