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Investigation and Classification of Treatable Traits in Patients With Chronic Airway Diseases

Recruitingn/aAges 20 Years - 75 YearsAllBeijing Chao Yang Hospital
NCT07472738 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This research study focuses on chronic airway diseases, such as Chronic Obstructive Pulmonary Disease (COPD) and asthma. These conditions make it difficult for patients to breathe, but breathing difficulty (dyspnea) is often perceived very differently. Some patients may feel severe distress with mild breathing problems, while others might not notice significant breathing issues even when lung function is poor. This difference in perception is termed "dyspnea perception." The main goal of this study is to understand how dyspnea perception varies among patients with chronic airway diseases. The investigators aim to determine if patients can be grouped into different subtypes based on the perception of breathing difficulties. The study will also investigate how these subtypes relate to other treatable characteristics, such as blood cell counts, allergy test results, and findings from lung

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📋 Eligibility rules (as published)
Inclusion Criteria: * Inclusion Criteria for Chronic Airway Disease Patients: 1. Age 20-75 years. 2. Meets the diagnostic criteria for COPD according to the 2022 GOLD guidelines OR meets the diagnostic criteria for asthma according to the 2022 GINA guidelines. 3. Willing and able to provide informed consent. * Inclusion Criteria for Healthy Controls: 1. Age ≥20 years. 2. No history of asthma symptoms or diagnosis of chronic respiratory diseases such as asthma or COPD. 3. Willing and able to provide informed consent and comply with the study protocol. Exclusion Criteria: * (applies to all participants): 1. Respiratory tract infection, COPD acute exacerbation, or asthma acute exacerbation within the past 3 months. 2. Presence of other diseases causing significant lung tissue destruction, such as severe bronchiectasis or tuberculosis. 3. History of thoracic or abdominal surgery within the past 3 months. 4. Heart rate \>120 beats per minute. 5. Ongoing anti-tuberculosis treatment. 6. Presence of other severe, uncontrolled systemic diseases. 7. Pregnant or lactating women.
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What it tests

  • Comprehensive Clinical Assessment
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Where

1 site
Beijing Chao-Yang Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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