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pEEG-Guided Anesthesia and Behavioral Outcomes in Children

RecruitingNAAges 3 Years - 10 YearsAllIstanbul University
NCT07473024 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Post-hospitalization behavioral changes are common in children after surgery and general anesthesia and may persist for varying durations depending on individual and perioperative factors. The Post-Hospitalization Behavior Questionnaire (PHBQ) is a well-validated instrument widely used to evaluate negative postoperative behavioral changes in pediatric patients following hospitalization or surgical procedures. Although early postoperative behavioral disturbances have been extensively studied, most research has focused on short-term outcomes within the first weeks after surgery, while long-term behavioral outcomes remain insufficiently investigated. Processed electroencephalography (pEEG) monitoring provides an objective method for assessing anesthetic depth during surgery. Parameters such as the Patient State Index (PSI) and Spectral Edge Frequency 95 (SEF95) allow dynamic evaluation of

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📋 Eligibility rules (as published)
Inclusion Criteria: * Children aged 3-10 years * Surgical duration longer than 1 hour * Patients undergoing urology, plastic surgery, or pediatric surgery procedures * Availability of early postoperative PHBQ data * Verbal consent from parents or legal guardians for participation in the follow-up telephone interview Exclusion Criteria: * Patients with neuromotor developmental abnormalities * History of epilepsy or antiepileptic medication use * Patients requiring postoperative intensive care unit admission * Emergency surgical procedures * Inability to contact the family or refusal of verbal consent for the telephone interview * Patients who underwent another surgical procedure between the initial surgery and the follow-up period
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What it tests

  • Processed EEG Monitoring
  • Standard Anesthesia Management
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Where

1 site
Istanbul University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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