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AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study

Recruitingn/aAges 20 Years - 43 YearsFemaleXinhua Hospital, Shanghai Jiao Tong University Scโ€ฆ
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In plain words

What the trial is, and whether it could suit you

The goal of this prospective cohort study is to enroll pregnancies complicated by placental-related fetal growth restriction (FGR) and to develop predictive models for adverse short- and long-term outcomes. This will be achieved by collecting novel intrauterine monitoring indicators along the fetal brain-placenta-heart axis, combined with conventional fetal surveillance parameters, in order to improve risk stratification and guide clinical management, ultimately improving pregnancy outcomes. The study will include pregnant women with singleton pregnancies complicated by isolated early-onset placental insufficiency-related FGR, preferably those with abnormal umbilical artery Doppler findings, who elect to continue the pregnancy. The main question it aims to answer is: โ€ข Whether a predictive model integrating novel intrauterine monitoring indicators along the fetal brain-placenta-heart

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Singleton pregnancy. * Isolated early-onset placental insufficiency-related fetal growth restriction (FGR), with priority given to cases with abnormal umbilical artery Doppler flow. * Pregnancies in which expectant management is continued. Exclusion Criteria: * Multiple pregnancy complicated by selective fetal growth restriction (sFGR). * FGR caused by fetal structural anomalies, genetic abnormalities, or intrauterine infection. * Twin pregnancy with intrauterine fetal demise (IUFD) of one fetus.
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What it tests

  • new ultrasound index and MRI
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Where

1 site
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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