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Factors Affecting Vaccine Prophylaxis Efficacy in Bone Marrow and Solid Organ Transplant Recipients: Impact on Infection and Mortality Rates

Recruitingn/aAges any - anyAllFondazione IRCCS Policlinico San Matteo di Pavia
NCT07473999 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Transplantation is one of the most challenging and complex areas of modern medicine. Besides the intrinsic complexity of the surgical and medical procedures, transplantation medicine must take into account a flawless medical management before and after transplant, especially because these patients represent a high-risk group for developing infectious complications that may be vaccine-preventable, with a high mortality rate. However, there is poor evidence regarding the effectiveness of the currently available vaccines in immunocompromised patients. The aim of this study, is the development of a specific healthcare pathway for the prevention of infectious diseases for patients referred to our Hospital who are eligible for solid organ transplantation (SOT) or bone marrow transplantation (BMT), thus improving the vaccination coverage of these patients, possibly reducing infection-related mo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Any patient eligible for SOT or BMT evaluated in our hospital * Only patients undergoing SOT or BMT will be followed-up for infections Exclusion Criteria: * Already enrolled in the study * Denied informed consent * Absolute contraindication to vaccinations
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What it tests

  • vaccine prophylaxis
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Where

1 site
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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