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Evaluation of Musculoskeletal Aging and Related Disorders Via Advanced Clinical Imaging

Recruitingn/aAges 18 Years - anyAllPeking University People's Hospital
NCT07474571 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Study Overview This clinical research focuses on the development and validation of a multimodal artificial intelligence (AI) platform designed for the automated diagnosis and precise staging of two major musculoskeletal conditions: Osteoporosis (OP) and Osteoarthritis (OA). By integrating diverse clinical imaging data, the study aims to provide a more objective and standardized approach to assessing bone and joint degeneration. Technological Core: Intelligent Staging Traditional diagnosis often relies on manual interpretation, which can lead to inter-observer variability. This study employs deep learning and multimodal imaging to: For Osteoporosis: Automatically quantify bone mineral density and micro-architectural changes to determine the stage of bone loss and evaluate fracture risk. For Osteoarthritis: Identify subtle radiological markers such as joint space narrowing and osteophy

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age: Adults aged at least 18 years. * Gender: No gender restrictions; both male and female participants are eligible. * Imaging Data: Participants must have completed relevant clinical imaging scans of skeletal sites, including but not limited to X-ray, CT (plain scan), or MRI (plain scan). * Anatomical Integrity: The skeletal structure of the target area must be free from congenital or acquired deformities. * Absence of Implants: No internal fixation materials or orthopedic implants in the skeletal areas being assessed. Exclusion Criteria: * Pathological History: Patients with a history of prior pathological fractures. * Malignancy: Patients seeking treatment or diagnosed with bone tumors or other systemic malignancies. * Medication History: Patients with a history of long-term steroid use, which may significantly affect bone density and joint structure. * Recent Treatment: Patients who have undergone radiotherapy or chemotherapy within the past six months. * Data Quality: Patients whose imaging data is of insufficient quality for AI analysis or lacks clear clinical diagnostic "gold standard" references (e.g., missing DXA results for osteoporosis staging).
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What it tests

  • No Interventions
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Where

1 site
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Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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