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Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy

RecruitingPhase 1, Phase 2Ages 25 Years - 65 YearsFemaleLiaquat National Hospital & Medical College
NCT07482709 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to know how effectively TAP block can reduce postoperative pain in total abdominal hystrectomy patients when given ketamine in addition to bupivacaine in TAP block and to compare it with the conventional TAP block with bupivacaine only. The main question it aims to answer is: Does intervention with ketamine in TAP block lowers the postoperative pain measured via visual analog scale and decreases the need for rescue analgesia? Patients will be assessed for pain in PACU( post anesthesia care unit), 6 hours, 12 hours and 24 hours postoperatively. Time of rescue analgesia will also be noted if given.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged between 25 to 60 years. * ASA grade I \& II. * Undergoing total abdominal hysterectomy. Exclusion Criteria: * BMI \>35kg/m2. * Patient refusal for participation. * Patients with coagulation disorders. * Patents with history of allergy and hypersensitivity to local anesthetic. * Patient having infection at the injection site. * Alcohol or drug abuse. * Cognitive or mental disorder.
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What it tests

  • bupivicaine 0.25%
  • bupivicaine 0.25% + ketamine
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Where

1 site
gynae operation theatre at Liaquat National Hospital
Karachi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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