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โ† Trials
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Valsalva SBP Drop and LVOT Obstruction

Recruitingn/aAges 18 Years - anyAllShanghai Zhongshan Hospital
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In plain words

What the trial is, and whether it could suit you

This study aimed to evaluate the efficacy of non-invasive dynamic blood pressure monitoring in assessing left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy. We prospectively collected SBP waveforms and LVOT gradient data from patients with obstructive and non-obstructive disease, systematically analyzed their correlation, and explored its clinical value in different clinical scenarios.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria:1: โ‘  Age โ‰ฅ 18 years 2: โ‘ก Diagnosed with hypertrophic cardiomyopathy (HCM) by echocardiography, with or without left ventricular outflow tract obstruction 3: โ‘ข Conscious and mentally competent, able to understand and voluntarily sign the informed consent form 4: โ‘ฃ Able to cooperate with the completion of provocation tests, non-invasive dynamic hemodynamic monitoring, and relevant follow-up examinations. \- Exclusion Criteria: * 1: โ‘  Age โ‰ค 18 years, or pregnant/lactating patients 2: โ‘ก Presence of other organic heart or great vessel diseases that cause left ventricular outflow tract obstruction, such as severe aortic stenosis, congenital subaortic membrane, etc. 3: โ‘ข Complicated with persistent atrial fibrillation or other severe arrhythmias that may affect the accuracy of hemodynamic monitoring 4: โ‘ฃ Previous history of interventional or surgical therapy for left ventricular outflow tract obstruction, including septal ablation or myectomy 5: โ‘ค Patients with other conditions considered inappropriate by the investigators (e.g., those with absolute or relative contraindications to provocation tests) 6: โ‘ฅ Patients currently participating in other clinical studies.
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What it tests

  • participants are not assigned an intervention as part of the study
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Where

1 site
Zhongshan Hospital
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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