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Effectiveness of Thoracoabdominal Nerve Block (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy

RecruitingNAAges 18 Years - 70 YearsFemaleIstinye University
NCT07483190 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to investigate the effectiveness of a specific regional anesthesia technique, the Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA), on reducing pain after laparoscopic hysterectomy surgery. Hysterectomy is a common major surgical procedure, and managing postoperative pain is crucial for patient comfort and faster recovery. Participants will be randomly assigned to one of two groups: The M-TAPA Group: Patients will receive the nerve block using a local anesthetic (bupivacaine) before the surgery begins. The Control Group: Patients will receive standard postoperative pain management without the nerve block. The primary goal is to determine if the M-TAPA block reduces the total amount of opioid (morphine) used by patients in the first 24 hours after surgery. The researchers will also evaluate pain scores (NRS), the time until the first requ

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged between 18 and 70 years * ASA (American Society of Anesthesiologists) physical status I, II, or III * Scheduled for elective laparoscopic hysterectomy * Voluntary participation with signed informed consent Exclusion Criteria: * Hepatic or renal disease. * Coagulation disorders. * Uncontrolled cardiovascular or respiratory diseases. * Psychiatric disorders. * History of allergy to local anesthetics. * History of alcoholism, drug or substance abuse. * Body Mass Index (BMI) greater than 35 kg/m2 * Refusal of the regional block procedure
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What it tests

  • Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA)
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Where

1 site
Istinye University Liv Hospital Bahcesehir
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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