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Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort

Recruitingn/aAges 60 Years - anyAllKorea University
NCT07485387 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea. The main questions it aims to answer are: Does daily psychological stress measured in real-time affect short-term and long-term cognitive function in older adults? Do pro-inflammatory cytokines (such as CRP, IL-6, IL-10, and TNF-ฮฑ) mediate the relationship between emotional stress and cognitive decline? How do social support and social isolation influence cognitive function and inflammatory biomarkers over time? Participants will: Complete baseline surveys assessing depression, cognitive function, and personal characteristics Use a smartphone app to answer brief surveys about their emotions, cognitive performance, and social interactions 1-6 times daily for two weeks Wear a Galaxy Watch

Sign in to get the eligibility rules as simple questions to take to your doctor.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults aged 60 or older residing in the Republic of Korea * Samsung Galaxy smartphone users capable of using smartphone applications * Sufficient cognitive ability to understand and follow research instructions (MMSE score of 21 or above) * For individuals who do not meet the cognitive criteria, those who understand the study procedures and provide informed consent along with their legal guardian Exclusion Criteria: * Diagnosis of dementia at baseline * Severe visual or hearing impairments that prevent participation in psychological assessments * Illiteracy that prevents participation in cognitive testing * Less than 80% compliance with the 2-day preliminary EMA protocol (one additional attempt allowed after re-training) * Current alcohol or substance abuse * Inability to ambulate or psychiatric conditions that prevent survey participation * Currently undergoing cancer treatment or received chemotherapy within the past 6 months
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What it tests

  • Not listed
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Where

1 site
Korea University
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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