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Magnetic Resonance Imaging of the Lung: Oncological Applications

Recruitingn/aAges 18 Years - anyAllFondazione IRCCS Policlinico San Matteo di Pavia
NCT07486219 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Lung neoplasms are characterized by a complex interaction between tumor cells and a variety of resident and infiltrating host elements, secreted factors, and extracellular matrix proteins, collectively referred to as the microenvironment. Nowadays, in the setting of lung cancer, and in particular non-small cell lung cancer (NSCLC), the evaluation of microenvironment characteristics can only be performed by a pathologist and only on histological material. By combining different MRI parameters, it may be possible to create a specific imaging "signature" for the three different immune phenotypes and thus be able to make a distinction based on MRI examination.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Primary NSCLC of the lung (TNM 8th edition T parameter ≥T1c) * Biopsy examination of the primary tumor adequate at least for PDL-1 quantification * Staging CT scan with uncertain N parameter and definite M parameter. Exclusion Criteria: * Absolute contraindications to magnetic resonance imaging or the administration of gadolinium-based contrast agents
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What it tests

  • Not listed
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Where

1 site
Fondazione IRCCS Policlinico San Matteo
Pavia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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