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Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana

RecruitingNAAges 18 Years - 45 YearsFemaleUniversity of Ghana Medical School
NCT07488091 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital. The main question it aims to answer is: In a before-and-after study design, we will test the hypothesis that multidisciplinary care for pregnant women with SCD in a non-academic hospital will result in a 50% relative risk reduction in mortality compared to the mortality rate in pregnant women with SCD in the same hospital before the multidisciplinary care. Participants will be managed using the academic hospital's multidisciplinary sickle cell disease obstetrics protocol adapted for the non-academic hospital

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📋 Eligibility rules (as published)
Inclusion criteria * Pregnant women with a confirmed laboratory diagnosis of sickle cell disease * Pregnancy confirmed by a pelvic ultrasound scan * Pregnancy should be 34 weeks' gestation or less * Pregnant women should be aged 18 - 45 years * Pregnant women should be attendants at the non-academic hospital Exclusion criteria * All pregnant women with sickle cell disease who do not provide informed consent * All pregnant women with sickle cell disease who are referred for management of acute complications and hospital admission * All pregnant women with sickle cell disease who are referred for labor and delivery * All pregnant women with SCD who plan on delivering outside the non-academic hospital and won't be able to adhere to the follow-up procedures during the puerperium (the first six weeks after childbirth)
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What it tests

  • Multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.
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Where

1 site
Greater Accra Regional Hospital
Accra, Ghana
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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