💬In plain words
What the trial is, and whether it could suit you
The goal of this clinical trial is to learn if Yiyang Huoluo Decoction (a custom Chinese herbal medicine) works safely and effectively to treat coronary heart disease with atherosclerosis in older adults. It also aims to find out how this herbal treatment may affect blood vessel health and repair at a cellular level.
The main questions it aims to answer are:
* Does adding Yiyang Huoluo Decoction to standard Western medical care improve symptoms and heart-related health in older adults with coronary heart disease and atherosclerosis?
* Is Yiyang Huoluo Decoction safe for older adults to take alongside their regular heart medications?
* How does this herbal treatment affect the damaged blood vessels in study participants?
Researchers will compare two groups of participants to see if the combined treatment works better than standard care alone.
Who can take part: Older adults diagnosed
Sign in to get the eligibility rules as simple questions to take to your doctor.
📋 Eligibility rules (as published)
Inclusion Criteria:
All of the following conditions must be met simultaneously for enrollment:
* ① Meet the diagnostic criteria for stable angina pectoris;
* ② Classified as Grade I to III according to the Canadian Cardiovascular Society (CCS) Angina Grading Scale;
* ③ Meet the diagnostic criteria for chest discomfort syndrome due to yang qi deficiency and decline (a traditional Chinese medicine pattern differentiation);
* ④ Aged between 50 and 75 years old;
* ⑤ Received drug-eluting stent implantation due to severe vascular stenosis (single artery ≥75%， or LM ≥50%) detected by coronary angiography;
* ⑥ Able to actively comply with medical instructions and voluntarily sign the written informed consent form.
Exclusion Criteria:
Participants will be excluded if they meet any of the following conditions:
* ① Diagnosed with acute coronary syndrome (including acute ST-segment elevation myocardial infarction, acute non-ST-segment elevation myocardial infarction, and unstable angina pectoris) after relevant examinations;
* ② Suffer from chest pain caused by non-cardiac diseases other than stable angina pectoris; or have complicated severe hypertension (systolic blood pressure ≥ 180mmHg and/or diastolic blood pressure ≥ 110mmHg), severe cardiopulmonary insufficiency, or malignant tumor;
* ③ Have severe endocrine, hematological or rheumatic immune system diseases, severe hepatic and renal dysfunction, active gastrointestinal bleeding, or mental illness;
* ④ Have an allergic constitution or a history of allergic reactions to traditional Chinese medicine;
* ⑤ Have incomplete major baseline data that may affect the trial results, or have participated in other clinical trials recently.
💊
What it tests
- Yiyang Huoluo Decoction
- conventional western medicine treatment
People's Hospital of Anji
Huzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
HealthTeky