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Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis

RecruitingNAAges 18 Years - anyAllUniversity Hospital, Montpellier
NCT07494942 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if a structured cardiac rehabilitation program can help people with cardiac amyloidosis improve their ability to exercise and their quality of life. The main questions it aims to answer are: Does cardiac rehabilitation raise peak oxygen uptake (VO₂ peak), which shows how well the heart and lungs work during exercise? Is cardiac rehabilitation safe and practical for people with cardiac amyloidosis? How does cardiac rehabilitation affect other exercise measures, heart function, symptoms linked to autonomic dysfunction, and quality of life? This study has no comparison group. Researchers will measure each participant's results before and after the rehabilitation program. Participants will: Complete a cardiac rehabilitation program for 5 weeks. Have tests before the program starts and again about 3 months later. These tests include: A cardiopu

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 or older * Cardiac ATTR amyloidosis diagnosed according to guidelines: Perugini grade II or III uptake on bone scintigraphy, without monoclonal gammopathy. * Ability to undergo a stress test * Available to complete the 5-week rehabilitation program within 30 days of the stress test Exclusion Criteria: * Uncontrolled ventricular arrhythmias * NYHA Class IV heart failure * Inability to give informed consent to participate in the study * Inability to monitor the patient during the study period * Subject not enrolled in a social security program or not eligible for such a program * Pregnant or breastfeeding women, patients unable to give consent, protected adults, vulnerable persons * Subjects deprived of liberty by judicial or administrative decision
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What it tests

  • Cardiac Rehabilitation Program
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Where

1 site
KRIEF
Montpellier, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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