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Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis

Recruitingn/aAges 18 Years - anyAllSanliurfa Education and Research Hospital
NCT07496723 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Acute appendicitis is one of the most common surgical emergencies, but diagnostic uncertainty may still lead to unnecessary appendectomy in some patients. This prospective observational study aims to evaluate the diagnostic performance of computed tomography (CT) reporting and the Appendicitis Inflammatory Response (AIR) score in adult patients undergoing appendectomy for suspected acute appendicitis. The primary objective is to determine the negative appendectomy rate based on final histopathology. Secondary objectives are to assess the agreement between AIR score, CT findings, intraoperative severity grading, and pathology results, and to explore diagnostic performance across patient subgroups. No study-specific intervention beyond routine clinical care will be performed.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older * Presentation to the emergency department with suspected acute appendicitis * Underwent computed tomography after clinical evaluation * Computed tomography report compatible with acute appendicitis * Underwent appendectomy for presumed acute appendicitis * Provided informed consent Exclusion Criteria: * Age younger than 18 years * Pregnancy * Planned additional surgical intervention in the same session for a reason other than appendicitis * Intraoperative finding of a non-appendiceal pathology requiring a different surgical procedure * Refusal to participate in the study
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What it tests

  • Not listed
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Where

1 site
Sanliurfa Education and Research Hospital
Sanliurfa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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